Mossman is located seventy-seven kilometres north of Cairns and seventeen kilometres north of Port Douglas.
Mossman itself is a small township and the majority of students come to the school by bus from the surrounding districts. The enrolment is approximately 660 students with 56 teachers on staff and 40 support staff.
Mossman State High School is located at 46-62 Front Street Mossman (on the right as you drive through Mossman from the south).